How can AI help us understand and master deeply complex systems—from the game Go, which has 10 to the power 170 possible positions a player could pursue, or proteins, which, on average, can fold in 10 to the power 300 possible ways? This week, Reid and Aria are joined by Demis Hassabis. Demis is a British artificial intelligence researcher, co-founder, and CEO of the AI company, DeepMind. Under his leadership, DeepMind developed Alpha Go, the first AI to defeat a human world champion in Go and later created AlphaFold, which solved the 50-year-old protein folding problem. He's considered one of the most influential figures in AI. Demis, Reid, and Aria discuss game theory, medicine, multimodality, and the nature of innovation and creativity.For more info on the podcast and transcripts of all the episodes, visit https://www.possible.fm/podcast/ Select mentions: Hitchhiker's Guide to the Galaxy by Douglas AdamsAlphaGo documentary: https://www.youtube.com/watch?v=WXuK6gekU1YNash equilibrium & US mathematician John Forbes NashHomo Ludens by Johan HuizingaVeo 2, an advanced, AI-powered video creation platform from Google DeepMindThe Culture series by Iain BanksHartmut Neven, German-American computer scientistTopics:3:11 - Hellos and intros5:20 - Brute force vs. self-learning systems8:24 - How a learning approach helped develop new AI systems11:29 - AlphaGo’s Move 3716:16 - What will the next Move 37 be?19:42 - What makes an AI that can play the video game StarCraft impressive22:32 - The importance of the act of play26:24 - Data and synthetic data28:33 - Midroll ad28:39 - Is it important to have AI embedded in the world?33:44 - The trade-off between thinking time and output quality36:03 - Computer languages designed for AI40:22 - The future of multimodality 43:27 - AI and geographic diversity 48:24 - AlphaFold and the future of medicine51:18 - Rapid-fire QuestionsPossible is an award-winning podcast that sketches out the brightest version of the future—and what it will take to get there. Most of all, it asks: what if, in the future, everything breaks humanity's way? Tune in for grounded and speculative takes on how technology—and, in particular, AI—is inspiring change and transforming the future. Hosted by Reid Hoffman and Aria Finger, each episode features an interview with an ambitious builder or deep thinker on a topic, from art to geopolitics and from healthcare to education. These conversations also showcase another kind of guest: AI. Each episode seeks to enhance and advance our discussion about what humanity could possibly get right if we leverage technology—and our collective effort—effectively.