FoundMyFitness
Rhonda Patrick, Ph.D.
A podcast about health, science, nutrition, aging, and fitness.
#098 How to Train According to the Experts
Download my “How to Train According to the Experts” guide Exercise is more than a tool for physical transformation—it's a cornerstone of longevity, metabolic resilience, and neurocognitive vitality. In this special episode, I’m joined by Brady Holmer, a distinguished exercise science communicator and lifelong endurance runner, as we deconstruct the latest evidence-based protocols for enhancing muscle strength and cardiovascular health. What’s the optimal exercise protocol to reverse 20 years of
#097 The Science of Protein and Its Role in Longevity, Cancer, Aging, and Building Muscle
Discover my premium podcast, The Aliquot Download my “How to Train According to the Experts” guide Protein is far more than a building block for muscle—it’s essential for metabolic health, insulin sensitivity, and preventing conditions like type 2 diabetes and sarcopenia. But how much do we truly need? And could too much protein, especially from meat, actually be harmful? This episode challenges the conventional RDA of 0.8 g/kg, presenting research that supports higher intakes of 1.2–2 g/kg for
#096 How to Improve Metabolic Health with HIIT, Circadian-Timed Eating, & Sleep
Discover my premium podcast, The Aliquot Learn how to choose the right omega-3 supplement in my free 13-page guide Exercise, meal timing, and sleep are three powerful tools for optimizing metabolic health, a key factor in healthy aging. Even slightly elevated blood glucose levels, but within the "normal" range, can contribute to brain atrophy in areas linked to aging and neurodegeneration. Long-term glucose elevations (high HbA1c) also promote harmful compounds that stiffen blood vessels, reduc
#095 What Microplastics Are Doing to Your Brain, Body, and Reproductive Systems
Sweating helps enhance microplastic-associated chemical excretion. Get my free sauna report when you sign up here for my newsletter. Discover my premium podcast, The Aliquot Every week, the average person ingests the equivalent weight of a credit card in plastic.* While certain preventive measures can significantly reduce your intake of these harmful substances, it’s crucial to acknowledge a more daunting concern: the bioaccumulation of microplastics in the brain, potentially at ten times the
#094 Dr. Layne Norton on Building Muscle – Insights on Diet, Training, and Supplements
Get my exact protocols for boosting levels of brain-derived neurotrophic factor (BDNF) and enhancing cognition Discover my premium podcast, The Aliquot Dr. Layne Norton is a Ph.D. in Nutritional Sciences, a professional bodybuilder, and a champion powerlifter. We discuss why most people aren’t training too hard, when to go to failure, whether seed oils are “the” central cause of chronic disease, why having a slow metabolism isn’t a credible reason for being overweight (for most), and the sustai
#093 Dr. Luc van Loon: Optimizing Protein Intake & Distribution for Muscle Growth
My free omega-3 guide (the ultimate blueprint for choosing a fish oil supplement) Discover my premium podcast, The Aliquot Dr. Luc van Loon is a renowned figure in the realm of exercise science, particularly celebrated for his deep understanding of protein metabolism, resistance training, and the nuanced role of collagen supplements in sports nutrition. Our conversation is an in-depth discussion on optimal protein intake & distribution strategies for stimulating muscle protein synthesis with de
#092 The Truth About Alcohol: Risks, Benefits, and Everything In-Between | Dr. Rhonda Patrick
My omega-3 guide on concerns like a-fib, dosage, supplement quality, oxidation, and more Discover my premium podcast, The Aliquot Join over 300,000 people and sign up for my newsletter Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A’s with Rhonda and more In this special solo episode of FoundMyFitness, we’re taking a deep dive into alcohol. We’ll explore the science, misconceptions, controversies, and health effects of this widely used drug. I beli
#091 Andrew Huberman, PhD: How to Improve Motivation & Focus By Leveraging Dopamine
Download the 12-Page "Omega-3 Supplementation Guide" Discover my premium podcast, The Aliquot Join over 300,000 people and sign up for my newsletter Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A’s with Rhonda and more Dr. Andrew Huberman is a Stanford professor, neurobiologist, and host of the incredibly popular Huberman Lab Podcast. He’s also the guest on this episode of the FoundMyFitness podcast. Our conversation encompasses an in-depth discu
#090 How Exercise Prevents & Reverses Heart Aging | Benjamin Levine, M.D.
Download the 13-Page "Omega-3 Supplementation Guide" Discover my premium podcast, The Aliquot Join over 300,000 people and sign up for my newsletter Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A’s with Rhonda and more Today's guest, Dr. Benjamin Levine, has shown that with the right exercise protocol, people who were sedentary most of their lives could reverse up to 20 years of heart aging. Dr. Levine is one of the world's leading experts in unde
#089 Why Exercise Intensity Matters for Longevity | CrossFit for Health 2024
Download the 9-Page "Cognitive Enhancement Blueprint" Discover my premium podcast, The Aliquot Join over 300,000 people and sign up for my newsletter Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A’s with Rhonda and more I recently had the privilege of presenting at the CrossFit Health Summit, where I explored a constellation of factors contributing to longevity. In this context, I placed a special emphasis on the pivotal role of vigorous exercise
#088 The Science of Optimizing Sleep - Special Preview
Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A’s with Rhonda and more Discover my premium podcast, The Aliquot If you’ve been following FoundMyFitness for a while, you may remember that we have our members-only podcast, The Aliquot. I want to share a preview of our newest Aliquot episode, "The Science of Optimizing Sleep," available to everyone, not just our Premium Members. Adequate, quality sleep is essential for the body's recovery and repair, p
#087 The Science of Magnesium and Its Role in Aging and Disease | Dr. Rhonda Patrick
Download the 9-Page "Cognitive Enhancement Blueprint" Discover my premium podcast, The Aliquot Join over 300,000 people and sign up for my newsletter Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A’s with Rhonda and more In this solo episode, I'm taking an in-depth look at magnesium – a critical yet frequently underestimated mineral in our health. Magnesium stands tall among vital nutrients for its significant role in multiple aspects of human phy
#086 How Micronutrients & Exercise Ameliorate Aging | Dr. Rhonda Patrick
Download the 9-Page "Cognitive Enhancement Blueprint" Discover my premium podcast, The Aliquot Join over 300,000 people and sign up for my newsletter Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A’s with Rhonda and more In today's episode, I'm bringing you along to the American Academy of Anti-Aging Medicine's Longevityfest Conference, where I had the honor of presenting a keynote last December. We'll explore some foundational yet effective tacti
#085 Dr. Peter Attia on Mastering Longevity – Insights on Cancer Prevention, Heart Disease, and Aging
Download the 9-Page "Cognitive Enhancement Blueprint" Discover my premium podcast The Aliquot Show notes are available by clicking here Peter Attia, MD is a highly respected expert in preventive medicine, focused on the crucial subject of longevity and cardiovascular health. He's also the author of the NY Times best selling book Outlive - which I highly recommend if you have not read it already. Peter's philosophy transcends the conventional goal of merely extending lifespan; it's about enric
#084 The Longevity & Brain Benefits of Vigorous Exercise | Dr. Rhonda Patrick
Download the 9-Page "Cognitive Enhancement Blueprint" companion guide at bdnfprotocols.com. This episode challenges common perceptions about exercise, delving deep into the benefits of vigorous exercise for not just physical health but also brain function, aging, and even cancer prevention. It tackles fundamental questions, like what genetic and metabolic adaptations occur with vigorous exercise and how it can contribute to combating heart's age-related changes. We also unpack how these rigorou
#083 How Vitamin D, Omega-3s, & Exercise May Increase Longevity | Dr. Rhonda Patrick
This episode features Rhonda Patrick, Ph.D., and was originally recorded for the Institute for Functional Medicine's podcast, 'Pathways to Wellbeing.' This episode outlines a series of fundamental tactics you can start applying immediately to enhance cellular health, protect the nervous system, elevate mood, reduce inflammation, promote muscle and bone function, and help prevent chronic disease. In this episode, I discuss: (00:00) Introduction (01:04) Vitamin D deficiency — risks, why it's so c
#082 The Science of Vigorous Exercise — Should We Train Hard or Train Long? | Martin Gibala, Ph.D.
Dr. Martin Gibala is a muscle physiologist, professor, and kinesiology department chair at McMaster University in Hamilton, Ontario, Canada. He is best known for pioneering research on the health benefits of high-intensity interval training (HIIT) and his profound understanding of HIIT's physiological mechanisms. He is a co-author of the book "The One-Minute Workout." In this episode, we discuss: (00:00) Introduction (11:00) What is high-intensity training? (11:53) Zone 2 vs. HIIT for VO2 max —
#081 The Anabolic Potential of Omega-3 Fatty Acids | Chris McGlory, PhD
Dr. Chris McGlory is an assistant professor at Queen's University in Kingston, Ontario, Canada. Known for his work in the field of muscle physiology and aging, Dr. McGlory's research focuses on elucidating the molecular mechanisms underlying muscle protein synthesis and degradation, with a particular emphasis on the roles that omega-3 fatty acids play in maintaining muscle health in older adults. In this episode, we discuss: (00:00) Introduction (05:50) Start of interview (13:03) Why atrophy is
#080 How Heat Therapy Improves Slow Wave Sleep
Heat therapy, such as using a sauna or soaking in a hot bath, may significantly improve your slow wave sleep. My latest episode delves into the fascinating intersection between exercise and passive body heating and elucidates how high energy expenditure exercise and heat exposure share nuanced mechanisms in sleep regulation. Some key aspects explored include: The surprising role of the immune system in regulating sleep through somnogenic cytokines, immune signals like IL-1B and TNF-alpha, relea
#079 Blood-Brain Barrier Dysfunction in Alzheimer’s Disease and Dementia | Axel Montagne, Ph.D.
Dr. Axel Montagne is a chancellor's fellow and group leader at the UK Dementia Research Institute at the University of Edinburgh Centre for Clinical Brain Sciences. His group aims to understand how, when, and where critical components of the blood-brain barrier become dysfunctional preceding dementia and in the earliest stages of age-related cognitive decline. With this knowledge, they hope to develop precise treatments targeting brain vasculature to protect brain function. More importantly his
#078 Resistance training for time efficiency, body composition, and maximum hypertrophy | Brad Schoenfeld, Ph.D.
Dr. Brad Schoenfeld is a professor at Lehman College in the Bronx, in New York City. His research primarily focuses on muscle adaptations to strength training, muscle hypertrophy. Publishing over 300 studies in the field of exercise and sports nutrition as a scientist, Brad began his career as a competitive bodybuilder and personal trainer. In this episode, we discuss: (00:00) Introduction to Dr. Brad Schoenfeld (05:26) Why should we lift weights? (06:56) Why building bone matters (11:33) How t
#077 Rewriting genomes to eradicate disease and aging | Dr. George Church
George Church, Ph.D. is a professor of genetics at Harvard Medical School and of health sciences and technology at both Harvard and the Massachusetts Institute of Technology. Dr. Church played an instrumental role in the Human Genome Project and is widely recognized as one of the premier scientists in the fields of gene editing technology and synthetic biology. In this episode, we discuss: (00:00) Introduction to Dr. George Church (07:13) History of the Human Genome Project (15:20) Manufacturi
#076 Building Muscle with Resistance Exercise and Reassessing Protein Intake | Stuart Phillips, PhD
Stuart Phillips, PhD, is a professor of kinesiology at McMaster University in Hamilton, Ontario, Canada, where he also serves as the director of the Physical Activity Centre of Excellence. His research centers on the roles exercise and nutrition play in influencing human skeletal muscle protein turnover and how these lifestyle factors influence body composition, especially as we age. In this episode, we discuss: (00:00) Introduction to Dr. Stuart Phillips (07:16) Why muscle is important for lon
#075 Intestinal Permeability: the Bacterial link to Aging, Brain Barrier Dysfunction & Metabolic Disorder
The intestinal barrier serves as a gatekeeper to the human body. The loss of the health and integrity of this barrier influences multiple aspects of human health – including cardiometabolic function, neurological health, behavior, and more – in surprising and unexpected ways. One of these ways involves lipopolysaccharide, or LPS, a bacterial product that arises in the intestine, and its interaction with far distal tissues and organs via the induction of immune mediators. Dr. Rhonda Patrick was
#074 Dr. Dominic D'Agostino on Developing a Well-Designed Ketogenic Diet and Harnessing Its Benefits
Dr. Dominic ("Dom") D'Agostino is an expert on a wide range of topics related to metabolic health, ketosis, and ketogenic diets. As one of the world's foremost experts on the ketogenic diet, Dom has personally practiced some variation of ketogenic diet for over a decade, bringing a substantial amount of practical experience along with his anecdotes from human and animal research. In this episode, we discuss: (00:00) Introduction to Dr. Dominic D'Agostino (04:59) What is "keto” (and what it is n
#073 Sauna Benefits Deep Dive and Optimal Use with Dr. Rhonda Patrick & MedCram
This episode features a discussion with MedCram co-founder Kyle Allred on the effects of sauna. I had the pleasure of being interviewed by Kyle on all things sauna science and we're posting that discussion for you here. As an exercise mimetic, sauna use has anti-inflammatory, mood-elevating, and detoxifying properties that research increasingly shows may deliver cardiovascular and brain benefits. The science of sauna use has been a research interest of mine for many years and this discussion is
#072 Morgan Levine, PhD, on PhenoAge and the Epigenetics of Age Acceleration — can we change the pace?
Morgan Levine, Ph.D., developed the phenotypic aging clock called PhenoAge and is a Founding Principal Investigator at Altos Labs, a biotech company that seeks to understand the mechanisms that drive the aging process and age-related diseases with the hope of identifying possible interventions. Additionally, Dr. Levine is an assistant professor of pathology at the Yale University School of Medicine, where her research focuses on the science of biological aging. Dr. Levine completed a postdoctora
#071 Peter Diamandis, MD, and Tony Robbins on strategies that promote longevity now – and in the very near future
Dr. Peter Diamandis is a serial entrepreneur and founder of XPRIZE, a non-profit organization that designs and conducts global competitions that incentivize the development of technological breakthroughs that propel humanity toward a better future. Tony Robbins is an entrepreneur, bestselling author, philanthropist, and business strategist. He provides business and life coaching to millions of people worldwide through his audio programs, educational videos, and live seminars. Diamandis and
#070 Dr. Eran Elinav on Microbiome Insights into Personalized Response to Diet, Obesity, and Leaky Gut
Eran Elinav, MD, PhD, is a professor of immunology and principal investigator at the Weizmann Institute of Science in Tel Aviv, Israel, where he co-directs the Personalized Nutrition Project. Dr. Elinav is also a principal investigator at the German Cancer Research Center in Heidelberg, Germany. His research focuses on understanding the complex interactions between humans and the bacteria that reside in their gut and how these interactions shape human health and disease. In this episode, Dr. Eli
#069 COVID Vaccine Myths, Questions, and Rumors with Rhonda Patrick and Roger Seheult
In this nearly 2.5-hour episode, Dr. Rhonda Patrick and Dr. Roger Seheult and Kyle Allred of MedCram make a thoughtful, merit-based, and truly comprehensive discussion of COVID-19 vaccination. In addition to being a co-founder of MedCram Medical Lectures, Dr. Roger Seheult is, as you will find out in the conversation, a boots on the ground, critical care pulmonologist. For Dr. Seheult, COVID-19 is not just theory. He sees real sick people and for that reason brings a very special context to this
#068 Dr. Bill Harris on the Omega-3 Index: Increasing Omega-3 to Promote Longevity & Transform Health
Dr. William ("Bill") Harris is one of the world's preeminent experts in the field of omega-3 fatty acid research. His work has focused on the roles that fatty acids in play in cardiovascular and neurocognitive health. The author of more than 300 scientific papers on fatty acids and health, Dr. Harris is a professor in the Department of Medicine in the Sanford School of Medicine at the University of South Dakota, the co-inventor of the Omega-3 Index, founder of OmegaQuant Analytics, and presiden
#067 Dr. Ashley Mason on Drug-free Approaches for Treating Depression, Insomnia, and Overeating
Dr. Ashley Mason is a clinical psychologist and director of the Sleep, Eating, and Affect Laboratory at the Osher Center for Integrative Medicine at UCSF. Her research centers on nonpharmacological approaches for treating depression, insomnia, and overeating. In this episode, we discuss: (00:00) Introduction (08:10) Whole-body hyperthermia (WBH) and sauna use differ (17:06) Depression causes thermoregulatory dysfunction – but sauna use may correct it (21:12) WBH and sauna use may reduce symptom
#066 Dr. Mark Mattson on the Benefits of Stress, Metabolic Switching, Fasting, and Hormesis
Dr. Mark Mattson Dr. Mark Mattson is a professor of neuroscience at the Johns Hopkins University School of Medicine and the former chief of the Neuroscience Research Laboratory at the National Institute on Aging. He's one of the most cited neuroscientists in the world, with more than 180,000 citations noted in the scientific literature. Dr. Mattson's work has advanced scientific understanding of brain aging and identified fundamental aspects of neurodegenerative disorders, including Alzheimer’s
#065 Dr. Satchin Panda on Circadian Insights into Exercise Timing, Melatonin Biology, and Peak Cognition
Dr. Satchin Panda Dr. Satchidananda (Satchin) Panda is a professor in the Regulatory Biology Laboratory at the Salk Institute for Biological Studies. Dr. Panda’s work focuses on chronobiology, the study of the day-night cycles that drive the multifaceted activities of the human body, using genetic, genomic, and biochemical approaches. He is an expert on circadian rhythms and a pioneer in the field of time-restricted eating. A priority for Dr. Panda when designing his studies is to identify stra
#064 Dr. Michael Snyder on Continuous Glucose Monitoring and Deep Profiling for Personalized Medicine
Michael Snyder Dr. Michael Snyder is the director for the Center for Genomics and Personalized Medicine at Stanford and a pioneer and advocate of "deep profiling." Deep profiling seeks to apply intelligent analysis to large data sets to yield specialized clinical insight, ranging from common consumer-grade wearables like Apple Watches to whole-body MRI, continuous glucose monitoring, and metabolomics. In this episode, we discuss: (00:00) Introduction to Dr. Michael Snyder (12:51) Continuous glu
Dr. Michael Snyder on Continuous Glucose Monitoring and Deep Profiling for Personalized Medicine
Dr. Michael Snyder is the director for the Center for Genomics and Personalized Medicine at Stanford and a pioneer and advocate of "deep profiling." Deep profiling seeks to apply intelligent analysis to large data sets to yield specialized clinical insight, ranging from common consumer-grade wearables like Apple Watches to whole-body MRI, continuous glucose monitoring, and metabolomics. Chapters: 00:12:51 - Continuous glucose monitors 00:31:04 - Lyme disease 00:34:00 - Predicting illness with s
#063 Dr. Roger Seheult from MedCram on COVID-19 Vaccines, Vitamin D, and Heat Hydrotherapy
Dr. Roger Seheult Dr. Roger Seheult is the co-creator of MedCram Videos. In the early days of the COVID-19 pandemic, MedCram emerged as a beacon of insight, providing continuing coverage and perspectives in an environment almost defined by information scarcity. What particularly excited me about the unique opportunity of this interview is that apart from Dr. Seheult being a unique voice of public scholarship during the early days of the pandemic, he's also a quadruple board-certified pulmonolo
Dr. Roger Seheult from MedCram on COVID-19 Vaccines, Vitamin D, and Heat Hydrotherapy
Dr. Roger Seheult is the co-creator of MedCram Videos. In the early days of the COVID-19 pandemic, MedCram emerged as a beacon of insight, providing continuing coverage and perspectives in an environment almost defined by information scarcity. What particularly excited me about the unique opportunity of this interview is that apart from Dr. Seheult being a unique voice of public scholarship during the early days of the pandemic, he's also a quadruple board-certified pulmonologist with deep expe
Dr. Steve Horvath on epigenetic aging to predict healthspan: the DNA PhenoAge and GrimAge clocks
Consistent patterns of age-based alterations in DNA methylation can be harnessed to estimate age, serving as a sort of "clock," the premise of which is truly remarkable: Predict a person's age (or even lifespan), based on chemical modifications to their DNA that reflect the biological life history of the organism. Dr. Steve Horvath has analyzed large data sets of DNA methylation profiles to derive an algorithm that accurately predicts a person's chronological age across multiple cells, tissues,
#062 Dr. Steve Horvath on epigenetic aging to predict healthspan: the DNA PhenoAge and GrimAge clocks
Steve Horvath Steve Horvath, PhD, is a professor of human genetics and biostatistics at UCLA's Fielding School of Public Health Dr. Steve Horvath has analyzed large data sets of DNA methylation profiles to derive an algorithm that accurately predicts a person's chronological age across multiple cells, tissues, and organs, and even mammalian species. He built on this algorithm to develop second-generation clocks that could predict time-to-death among people of the same chronological age, as well
#061 Q&A with Dr. Jed Fahey on Sulforaphane, Moringa and Chemoprotection
Dr. Jed Fahey In this special two-hour Q&A episode with Dr. Jed Fahey, a world-leading expert on the science of chemoprotection and, in particular, sulforaphane, we discuss many of the listener-submitted questions from the hundreds of live event participants. In this episode, we discuss: (00:00) Introduction (07:19) The minimum daily dose of sulforaphane (12:04) Gauging sulforaphane content of foods is challenging (17:37) Workarounds to enhance the sulforaphane in cooked foods (23:38) How oft
Q&A with Dr. Jed Fahey on Sulforaphane, Moringa and Chemoprotection
In this special two-hour Q&A episode with Dr. Jed Fahey, a world-leading expert on the science of chemoprotection and, in particular, sulforaphane, we discuss many of the listener-submitted questions from the hundreds of live event participants. Get the full timeline and show notes. Listen to learn Dr. Fahey's thoughts on… 00:07:19 - The minimum daily dose of sulforaphane that elicits beneficial health effects 00:12:04 - Why gauging the amount of sulforaphane in foods presents challenges 00:17
Dr. Giselle Petzinger on Exercise for Parkinson's Disease
Giselle Petzinger, MD, an associate professor of Neurology at the University of Southern California and today’s guest, studies the extensive effects of how different types of exercise, in particular skill-based exercise, can affect the clinical outcome for people with Parkinson’s disease. Dr. Petzinger's work focuses on understanding how to promote brain repair after injury, particularly in the context of Parkinson's disease. She is currently investigating ways to enhance neuroplasticity in a pr
#060 Dr. Giselle Petzinger on Exercise for Parkinson's Disease
Giselle Petzinger Giselle Petzinger, MD, an associate professor of Neurology at the University of Southern California, studies the extensive effects of how different types of exercise, in particular skill-based exercise, can affect the clinical outcome for people with Parkinson’s disease. Dr. Petzinger's work focuses on understanding how to promote brain repair after injury, particularly in the context of Parkinson's disease. She is currently investigating ways to enhance neuroplasticity in a pr
Aliquot #3: Q&A Mashup - Fasting
Get a sample of our new premium member's content, known as Aliquots, by listening to this in-depth Q&A mashup on Fasting. What's an aliquot, you may ask? Aliquots are special, curated segments prepared and distributed to premium members via the premium members podcast feed. This collection of clips covers a range of topics related to fasting, including associated mechanisms of healthspan and longevity, purported health benefits, and when and how to break the fast. Episode Highlights 00:01:36 -
#059 Aliquot #3: Q&A Mashup - Fasting
Get a sample of our new premium member's content, known as Aliquots, by listening to this in-depth Q&A mashup on Fasting. What's an aliquot, you may ask? Aliquots are special, curated segments prepared and distributed to premium members via the premium members' podcast feed. In this previous, you'll learn: (00:00) Introduction (01:48) Fasting supports a healthy gut microbiome and reduces autoimmunity (08:28) Increasing autophagy with fasting (13:26) Reducing protein acetylation with fasting mi
Aliquot #2: Q&A Mashup - Sauna
Get a sample of our new premium member's content, known as Aliquots, by listening to this in-depth Q&A mashup on Sauna use. What's an aliquot, you may ask? Aliquots are special, curated segments prepared and distributed to premium members via the premium members podcast feed. This collection of clips covers some of the many health benefits associated with sauna use, including heat shock protein activation, cardiovascular health, muscle mass preservation, and more. Episode Highlights 00:07:00 -
#058 Aliquot #2: Q&A Mashup - Sauna
Get a sample of our new premium member's content, known as Aliquots, by listening to this in-depth Q&A mashup on Sauna use. What's an aliquot, you may ask? Aliquots are special, curated segments prepared and distributed to premium members via the premium members podcast feed. In this episode, you'll learn: (00:00) Introduction (01:41) Evidence supporting sauna use for health (04:09) How Finnish humid saunas can reduce viral illness (08:40) Sauna and hot bath use during the COVID-19 pandemic (15
Aliquot #1: Q&A Mashup - Pregnancy and child development
Get a sample of our new premium member's content, known as Aliquots, by listening to this in-depth Q&A mashup on pregnancy and child development. What's an aliquot, you may ask? Aliquots are special, curated segments prepared and distributed to premium members via the premium members podcast feed. This particular collection of segments covers every single major discussion of pregnancy and child development spanning years of members-only Q&As. Just for a few examples, it covers... My pre-pregna
#057 Aliquot #1: Q&A Mashup - Pregnancy and child development
Get a sample of our new premium member's content, known as Aliquots, by listening to this in-depth Q&A mashup on pregnancy and child development. What's an aliquot, you may ask? Aliquots are special, curated segments prepared and distributed to premium members via the premium members podcast feed. This particular collection of segments covers every single major discussion of pregnancy and child development spanning years of members-only Q&As. In this episode, you'll hear: (00:00) Introducing "
#056 The Biology of Breast Milk
This episode aims to be the most comprehensive video compendium on the biology of breast milk ever recorded. In this episode, you'll discover: (00:00) Introduction (07:11) Breast milk production and composition (09:59) Human milk oligosaccharides help establish the infant gut microbiome (16:32) Omega-3s in breast milk boost brain development (18:15) Vitamins and minerals in breast milk (22:05) Breast milk stem cells and multi-organ microchimerism (22:54) Harmful substances transferred to infant
The Biology of Breast Milk
This episode aims to be the most comprehensive compendium on the biology of breast milk ever recorded. Looking at the converging clinical and animal evidence of the impact of breast milk paints a complex and beautiful mosaic of developmentally supportive effects that range from allowing the mother to act as a “compensatory” immune system to possibly supporting the development of entire organ systems through the integration of maternal stem cells found in breast milk. Episode Highlights 00:07:11
#055 COVID-19 Q&A #2 - Antibody-Dependent Enhancement, Cross-Immunity, Immunity Duration & More
This is a continuation of the last episode where Dr. Patrick took questions from newsletter subscribers around the ongoing pandemic and tried to add value by talking about some of the recent research, among other things. In this episode, you'll discover: (00:00) Introduction (04:06) Data surrounding SARS-CoV-2 duration (06:30) SARS-CoV-2 and long-lasting immunity (11:27) Genetic causes of immune variation (14:27) Previous viral exposure and cross-immunity to SARS-CoV-2 (18:57) Antibody-dependen
COVID-19 Q&A #2 - Antibody-Dependent Enhancement, Cross-Immunity, Immunity Duration & More
This is a continuation of the last episode where Dr. Patrick took questions from newsletter subscribers around the on-going pandemic and tried to add value by talking about some of the recent research, among other things. Some of the topics that came up as a result of the questions submitted include: 00:04:03 - Data surrounding SARS-CoV-2 duration 00:06:37 - SARS-CoV-2 and potential immunity 00:11:35 - Some of the main factors known to play a role in immune variation 00:12:05 - What role ge
#054 Vitamin C: Oral vs. Intravenous, Immune Effects, Cancer, Exercise Adaptation & More
In this episode, Dr. Rhonda Patrick discusses all things vitamin C. This episode covers oral bioavailability, intravenous vitamin C bioavailability, immune cell function, common cold and other viral infections, lung function, sepsis, pneumonia, inflammation, intravenous vitamin C and cancer, role in exercise, safety concerns, and so, so much more! In this episode, you'll discover: (00:00) Introduction (07:33) Background on vitamin C, an antioxidant and immune booster (17:09) Bioavailability of
Vitamin C: Oral vs. Intravenous, Immune Effects, Cancer, Exercise Adaptation & More
In this episode, Dr. Rhonda Patrick discuss all things vitamin C. This episode covers oral bioavailability, intravenous vitamin C bioavailability, immune cell function, common cold and other viral infections, lung function, sepsis, pneumonia, inflammation, intravenous vitamin C and cancer, role in exercise, safety concerns, and so, so much more! Episode Timeline (abridged) 00:07:33 - Background on vitamin C 00:17:09 - Bioavailability of vitamin C [including dosing frequency] 00:22:53 - Vitamin
COVID-19 Q&A #1 with Rhonda Patrick, Ph.D.
This episode features Dr. Rhonda Patrick answering some of the most popular questions related to COVID-19. Look for another COVID-19-focused Q&A, coming soon. Some of the questions we selected from the batch to cover in this episode include: 00:02:36 - Are children and infants susceptible to COVID-19? Are some more susceptible to a more severe form of the disease? Are they carriers of it and possibly spreading transmission? 00:11:00 - Can you explain a little about hydroxychloroquine as poss
#053 COVID-19 Q&A #1 with Rhonda Patrick, Ph.D.
This episode features Dr. Rhonda Patrick answering some of the most popular questions related to COVID-19. Look for another COVID-19-focused Q&A, coming soon. In this episode, you'll discover: (00:00) Introduction (02:37) Are children and infants susceptible to COVID-19? Are some more susceptible to a more severe form of the disease? Are they carriers of it and possibly spreading transmission? (11:00) Can you explain a little about hydroxychloroquine as possibly treating COVID-19? How does it
New Omega-3, sulforaphane research, and more! [Kevin Rose Show]
This episode was originally recorded for The Kevin Rose Show. Given some of the unique discussions we had, I had no choice but to ask the great Kevin Rose if he would let me re-post it over here on the FoundMyFitness podcast feed. A request which he graciously obliged. In this episode, we discuss... 00:08:00 - Omega-3 00:27:23 - Metformin 00:50:05 - Sulforaphane 01:06:57 - Magnesium L-Threonate 01:13:44 - Sauna 01:23:48 - New FMF Membership Learn more about the new premium membership. Learn m
#052 New Omega-3, sulforaphane research, and more! [Kevin Rose Show]
This episode was originally recorded for The Kevin Rose Show. Given some of the unique discussions we had, I had no choice but to ask the great Kevin Rose if he would let me re-post it over here on the FoundMyFitness podcast feed. A request which he graciously obliged. In this episode, you'll discover: 00:00:00 - Introduction 00:08:00 - Increasing omega-3 levels in the brain with phospholipid DHA 00:27:23 - Metformin's effects on longevity and possible harms 00:48:23 - Fasting and NAD+ supplem
Is Resveratrol a Longevity Compound?
In this episode, Rhonda gives a summary of the science of resveratrol including its effects in animals and humans, mechanisms, and the bottom line on resveratrol supplementation and safety. Learn more about resveratrol at our comprehensive overview Relevant timepoints... 00:03:39 - Clinical effects of resveratrol in humans 00:04:10 - Effects on cardiovascular health biomarkers in humans 00:06:54 - Reduction of inflammatory biomarkers in humans 00:08:11 - Improved cognition and memory in clinica
#051 Is Resveratrol a Longevity Compound?
Rhonda gives a summary of the science of resveratrol including its effects in animals and humans, mechanisms, and the bottom line on resveratrol supplementation and safety. In this episode, you’ll discover: (00:00) Introduction (03:39) Resveratrol improves cardiovascular biomarkers in clinical trials (06:49) Anti-inflammatory effects of resveratrol (08:11) Improved cognition and memory in clinical studies (11:23) Resveratrol improved healthspan, but not lifespan, in animals (12:28) Induction
#050 NAD+ in Aging: Role of Nicotinamide Riboside and Nicotinamide Mononucleotide
In this episode, Rhonda describes NAD+ (perhaps one of the most important molecules in the human body), why it is so important for aging, and why it declines with age. In this episode, you'll discover: (00:00) Introduction (03:07) Overview of NAD+, a source of cellular energy (09:18) NAD+ fuels PARP and sirtuin enzymes, promoting longevity (12:37) How can I raise NAD+ levels? (17:03) Can NAD+ boosters (NMN & NR) promote cancer growth? (19:15) Making sense of the research so far (27:03) Why
NAD+, Nicotinamide Riboside, and Nicotinamide Mononucleotide with Rhonda Patrick
In this episode, Rhonda describes NAD+ (perhaps one of the most important molecules in the human body), why it is so important for aging, and why it declines with age. She discusses some of the popular NAD+ boosters like nicotinamide riboside and nicotinamide mononucleotide, explains what the animal and human data say, discusses some of the concerns associated with using these boosters, and provides some concluding thoughts. Learn more about NAD+ Learn more about nicotinamide riboside Learn mo
Dr. David Sinclair on Informational Theory of Aging, Nicotinamide Mononucleotide, Resveratrol & More
David A. Sinclair, PhD, is a professor in the Department of Genetics at Harvard Medical School and co-director of the Paul F. Glenn Center for the Biological Mechanisms of Aging. He is the co-founder of the journal Aging, where he serves as co-chief editor. Dr. Sinclair's work focuses on understanding the mechanisms that drive human aging and identifying ways to slow or reverse aging's effects. In particular, he has examined the role of sirtuins in disease and aging, with special emphasis on how
#049 Dr. David Sinclair on Informational Theory of Aging, Nicotinamide Mononucleotide, Resveratrol & More
David A. Sinclair David A. Sinclair, PhD, is a professor in the Department of Genetics at Harvard Medical School and co-director of the Paul F. Glenn Center for the Biological Mechanisms of Aging. He is the co-founder of the journal Aging, where he serves as co-chief editor. Dr. Sinclair's work focuses on understanding the mechanisms that drive human aging and identifying ways to slow or reverse aging's effects. In particular, he has examined the role of sirtuins in disease and aging, with speci
Sauna Use as an Exercise Mimetic for Heart and Healthspan
This podcast is the audio from a presentation Dr. Rhonda Patrick gave on how the sauna may be an exercise mimetic for heat health and healthspan. Sauna use has emerged as a means to increase lifespan and improve overall health, based on compelling data from observational, interventional, and mechanistic studies. Listen in to find out more. Click here to get the episode show notes and video. Watch the episode with cardiologist and sauna scientist Dr. Jari Laukkanen. Did you enjoy this podcast? It
#048 Sauna Use as an Exercise Mimetic for Heart and Healthspan
This podcast is the audio from a presentation Dr. Rhonda Patrick gave on how the sauna may be an exercise mimetic for heat health and healthspan. Sauna use has emerged as a means to increase lifespan and improve overall health, based on compelling data from observational, interventional, and mechanistic studies. Listen in to find out more. In this episode, you'll discover: (00:00) Introduction (03:01) Clinical research shows that sauna improves cardiovascular health (09:19) Finnish sauna vs Wa
Exercise as a Treatment for Depression
In this short episode, Dr. Patrick discusses some of the compelling science including observational studies, randomized controlled trials, and human mechanistic studies that suggests exercise is a powerful tool for preventing or managing the symptoms of depression and mental illness. Moreover, she talks about the specific types of exercise and exercise parameters that evidence suggests might be the most helpful for depression. This podcast started its life as a video, so make sure to check out t
#047 Exercise as a Treatment for Depression
In this short episode, Dr. Patrick discusses some of the compelling science including observational studies, randomized controlled trials, and human mechanistic studies that suggests exercise is a powerful tool for preventing or managing the symptoms of depression and mental illness. Moreover, she talks about the specific types of exercise and exercise parameters that evidence suggests might be the most helpful for depression. This podcast started its life as a video, so make sure to check out t
Dr. Elissa Epel on Telomeres and the Role of Stress Biology in Cellular Aging
Elissa Epel, PhD, is a Professor in the Department of Psychiatry at the University of California, San Francisco where she serves as the director of the Aging, Metabolism, and Emotions Center. Her research centers on the mechanisms of healthy aging and the associations between stress, telomere length, addiction, eating, and metabolic health. In this episode, we dive deep into the world of telomeres, the length of which is one of the useful biomarkers scientists have for getting a sense of the dif
#046 Dr. Elissa Epel on Telomeres and the Role of Stress Biology in Cellular Aging
Elissa Epel Elissa Epel, PhD, is a Professor in the Department of Psychiatry at the University of California, San Francisco where she serves as the director of the Aging, Metabolism, and Emotions Center. Her research centers on the mechanisms of healthy aging and the associations between stress, telomere length, addiction, eating, and metabolic health. In this episode, we dive deep into the world of telomeres, the length of which is one of the useful biomarkers scientists have for getting a sens
#045 Dr. Matthew Walker on Sleep for Enhancing Learning, Creativity, Immunity, and Glymphatic System
Matthew Walker Matthew Walker, Ph.D., is a professor of neuroscience and psychology at the University of California, Berkeley, and serves as the Director of the Center for Human Sleep Science. Walker's research examines the impact of sleep on human health and disease. One area of interest focuses on identifying "vulnerability windows" during a person's life that make them more susceptible to amyloid-beta deposition from loss of slow wave sleep and, subsequently, Alzheimer's disease later in li
Fasting Q&A with Dr. Rhonda Patrick and Mike Maser
This episode features a Q&A session with Dr. Rhonda Patrick. The questions were sourced from social media followers of both FoundMyFitness and also Zero Fasting Tracker, a convenient mobile app used widely in the fasting community for logging. In this 45-minute podcast, Dr. Patrick answers some of the most popular questions related to fasting, including: What effects coffee, supplements, and amino acids have on fasting Whether one method of fasting is more beneficial than others What effect the
#044 Fasting Q&A with Dr. Rhonda Patrick and Mike Maser
This episode features a Q&A session with Dr. Rhonda Patrick. The questions were sourced from social media followers of both FoundMyFitness and also Zero Fasting Tracker, a convenient mobile app used widely in the fasting community for logging. In this 45-minute podcast, Dr. Patrick answers some of the most popular questions related to fasting, including: (00:00) Introduction (03:46) What effects do coffee, supplements, and amino acids have on fasting? (12:29) Should you consume electrolytes on
Dr. Dale Bredesen on Preventing and Reversing Alzheimer's Disease
Dale E. Bredesen, M.D., is a professor of neurology at the Easton Laboratories for Neurodegenerative Disease Research at the David Geffen School of Medicine at the University of California, Los Angeles (UCLA). Dr. Bredesen's laboratory focuses on identifying and understanding basic mechanisms underlying the neurodegenerative process and the translation of this knowledge into effective treatments for Alzheimer's disease and other neurodegenerative conditions. He has collaborated on the publicatio
#043 Dr. Dale Bredesen on Preventing and Reversing Alzheimer's Disease
Dale E. Bredesen Dale E. Bredesen, M.D., is a professor of neurology at the Easton Laboratories for Neurodegenerative Disease Research at the David Geffen School of Medicine at the University of California, Los Angeles (UCLA). Dr. Bredesen's laboratory focuses on identifying and understanding basic mechanisms underlying the neurodegenerative process and the translation of this knowledge into effective treatments for Alzheimer's disease and other neurodegenerative conditions. He has collaborated
#042 Dr. Valter Longo on Resetting Autoimmunity and Rejuvenating Systems with Prolonged Fasting & the FMD
Dr. Valter Longo Dr. Longo is the current director of the longevity institute at the University of Southern California and also director of the Oncology and Longevity Program at the Institute of Molecular Oncology Foundation in Milan, Italy. Dr. Longo’s research focuses understanding the biological mechanisms that regulate the aging process, the role of fasting and diet in longevity and healthspan in humans as well as metabolic fasting therapies for the treatment of human diseases. In this epis
Dr. Valter Longo on Resetting Autoimmunity and Rejuvenating Systems with Prolonged Fasting & the FMD
This podcast is a spectacular round two podcast with Dr. Valter Longo. Dr. Longo is the current director of the longevity institute at the University of Southern California and also director of the Oncology and Longevity Program at the Institute of Molecular Oncology Foundation in Milan, Italy. Dr. Longo’s research focuses understanding the biological mechanisms that regulate the aging process, the role of fasting and diet in longevity and healthspan in humans as well as metabolic fasting therap
#041 Dr. Charles Raison on Depression, the Immune-Brain Interface & Whole-Body Hyperthermia
Charles Raison Charles Raison, M.D. is a professor at the School of Human Ecology at the University of Wisconsin-Madison and Founding Director of the Center for Compassion Studies in the College of Social and Behavioral Sciences at the University of Arizona. Dr. Raison’s research focuses on inflammation and the development of depression in response to illness and stress. He also examines the physical and behavioral effects of compassion training on the brain, inflammatory processes, and behavior
Dr. Charles Raison on Depression, the Immune-Brain Interface & Whole-Body Hyperthermia
Charles Raison, M.D. is a professor at the School of Human Ecology at the University of Wisconsin-Madison and Founding Director of the Center for Compassion Studies in the College of Social and Behavioral Sciences at the University of Arizona. Dr. Raison’s research focuses on inflammation and the development of depression in response to illness and stress. He also examines the physical and behavioral effects of compassion training on the brain, inflammatory processes, and behavior as well as the
Dr. Eric Verdin on Ketogenic Diet Longevity, Beta-Hydroxybutyrate & HDAC Inhibitors
Eric M. Verdin, M.D. is the fifth president and chief executive officer of the Buck Institute for Research on Aging and is a professor of Medicine at UCSF. Dr. Verdin's laboratory focuses on the role of epigenetic regulators in the aging process, the role of metabolism and diet in aging and on the chronic diseases of aging, including Alzheimer’s, proteins that play a central role in linking caloric restriction to increased healthspan, and more recently a topic near and dear to many of you, ketog
#040 Dr. Eric Verdin on Ketogenic Diet Longevity, Beta-Hydroxybutyrate & HDAC Inhibitors
Eric M. Verdin Eric M. Verdin, M.D. is the fifth president and chief executive officer of the Buck Institute for Research on Aging and is a professor of Medicine at UCSF. Dr. Verdin's laboratory focuses on the role of epigenetic regulators in the aging process, the role of metabolism and diet in aging and on the chronic diseases of aging, including Alzheimer’s, proteins that play a central role in linking caloric restriction to increased healthspan, and more recently a topic near and dear to man
Dr. Satchin Panda on Practical Implementation of Time-Restricted Eating & Shift Work Strategies
This is a nearly 2-hour round 2 episode with none other than Dr. Satchin Panda of the Salk Institute! At nearly two hours of dialog, this episode touches on a lot of material but has a special focus on practical implementation of time-restricted eating. Put another way, I kept a list of a lot of questions that seem to keep coming up and present them directly to Satchin. We talk about dealing with shift work, black coffee when fasting, and some of the distinctions between Satchin's approach to ti
#039 Dr. Satchin Panda on Practical Implementation of Time-Restricted Eating & Shift Work Strategies
Dr. Satchin Panda Dr. Satchidananda (Satchin) Panda is a professor in the Regulatory Biology Laboratory at the Salk Institute for Biological Studies. We talk about dealing with shift work, black coffee when fasting, and some of the distinctions between Satchin's approach to time-restricted eating which is influenced by his deep background in circadian biology and more conventional protocols like 16:8 that many people are familiar with. In addition to these important and very practical how-to tid
#038 Dr. Guido Kroemer on Autophagy, Caloric Restriction Mimetics, Fasting & Protein Acetylation
Dr. Guido Kroemer Dr. Guido Kroemer is a professor at the University of Paris Descartes and an expert in immunology, cancer biology, aging, and autophagy. He is one of the most highly cited authors in the field of cell biology and was the most highly cited cell biologist for the period between 2007 and 2013. Especially notable among his contributions: he was the first to discover that the permeabilization of mitochondrial membranes is a concrete step towards apoptotic cell death. In this episode
Dr. Guido Kroemer on Autophagy, Caloric Restriction Mimetics, Fasting & Protein Acetylation
Dr. Guido Kroemer is a professor at the University of Paris Descartes and an expert in immunology, cancer biology, aging, and autophagy. He is one of the most highly cited authors in the field of cell biology and was the most highly cited cell biologist for the period between 2007 and 2013. Especially notable among his contributions: he was the first to discover that the permeabilization of mitochondrial membranes is a concrete step towards apoptotic cell death. This episode is decidedly focused
#037 Dr. Jari Laukkanen on Sauna Use for the Prevention of Cardiovascular & Alzheimer’s Disease
Jari Laukkanen This podcast features Jari Laukkanen, M.D., Ph.D., a cardiologist and scientist at the Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio. Dr. Laukkanen has been conducting long-term trials looking at the health effects of sauna use in a population of over 2,000 middle-aged men in Finland. In this episode, you’ll discover: (00:00) Introduction (01:50) Sauna use improves cardiovascular health and reduces risk of death (06:42) How sauna use l
Dr. Jari Laukkanen on Sauna Use for the Prevention of Cardiovascular & Alzheimer’s Disease
This podcast features Jari Laukkanen, M.D., Ph.D., a cardiologist and scientist at the Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio. Dr. Laukkanen has been conducting long-term trials looking at the health effects of sauna use in a population of over 2,000 middle-aged men in Finland. The results? Massive reductions in mortality and memory disease in a dose-response fashion at 20-year follow-up. In this almost 25-minute episode, we talk about... 00:00
Judith Campisi, Ph.D. on Cellular Senescence, Mitochondrial Dysfunction, Cancer & Aging
Dr. Judith Campisi is a professor of biogerentology at the Buck Institute for Research on Aging and a co-editor in chief of the Aging Journal. As an expert on cellular senescence, the discussion involves a lot of talk about aging and cancer, where senescence plays a very important fundamental role. What are some of the strategies we might use in the future to prevent senescent cells? What causes them in the first place? In this 1-hour long conversation, we discuss a great number of very interes
#036 Judith Campisi, Ph.D. on Cellular Senescence, Mitochondrial Dysfunction, Cancer & Aging
Dr. Judith Campisi is a professor of biogerentology at the Buck Institute for Research on Aging and a co-editor in chief of the Aging Journal. As an expert on cellular senescence, the discussion involves a lot of talk about aging and cancer, where senescence plays a very important fundamental role. What are some of the strategies we might use in the future to prevent senescent cells? What causes them in the first place? In this episode, you’ll discover: (00:00) Introduction (05:12) Fundamenta
Gordon Lithgow, Ph.D. on Protein Aggregation, Iron Overload & the Search for Longevity Compounds
Dr. Gordon Lithgow of the Buck Institute for Research on Aging tells us about worms! Well, more accurately, his lab does research on nematodes, particularly an animal known as C. elegans. This unassuming scientific model has a lot of important advantages for science: they can be frozen and subsequently thawed and retain viability, they are extremely well understood down to the precise number of cells in their body and the wiring of their nervous system, known as the connectome. Additionally, the
#035 Gordon Lithgow, Ph.D. on Protein Aggregation, Iron Overload & the Search for Longevity Compounds
Dr. Gordon Lithgow of the Buck Institute for Research on Aging tells us about worms! This unassuming scientific model has a lot of important advantages for science: they can be frozen and subsequently thawed and retain viability, they are extremely well understood down to the precise number of cells in their body and the wiring of their nervous system, known as the connectome. Additionally, they have a short lifespan and are cheap to work with. Why would that be advantageous, you may ask? This i
#034 Refined Sugar and Its Effects on Mortality, the Brain, Cancer, Hormones & More
If you're anything like me, having the facts straight can sometimes help you to push through the tough part of building new habits or breaking old bad ones. This podcast talks about the realities of what the science says surrounding the consumption of refined sugar. Some of the facts may surprise you! In this episode, you'll discover: (00:00) Introduction (01:16) Excess sugar consumption is common and dangerous (05:16) Sugar accelerates the aging process itself (09:14) Refined sugar harms the b
Refined Sugar and Its Effects on Mortality, the Brain, Cancer, Hormones & More
If you're anything like me, having the facts straight can sometimes help you to push through the tough part of building new habits or breaking old bad ones. This podcast talks about the realities about what the science says surrounding the consumption of refined sugar. Some of the facts may surprise you! We talk about the relationship of consumption of refined sugar with... mortality and aging brain function, memory, and neuroinflammation the development of cancer and expression of oncogenes se
Does Saturated Fat Cause Heart Disease?
Today we try to answer or at least explore a big question in the world of health: does saturated fat cause heart disease? This is not an unreasonable concern given the fact that there have been several associative studies that have found a link between saturated fat and heart disease, which is, no doubt, a fat that we find abundantly in the typical American diet since it is richly found in staples like fatty beef, pork, butter, cheese, and other dairy products. And if you're in the United States
#033 Does Saturated Fat Cause Heart Disease?
Today we try to answer or at least explore a big question in the world of health: does saturated fat cause heart disease? This is not an unreasonable concern given the fact that there have been several associative studies that have found a link between saturated fat and heart disease, which is, no doubt, a fat that we find abundantly in the typical American diet since it is richly found in staples like fatty beef, pork, butter, cheese, and other dairy products. And if you're in the United States
Does Meat Consumption Cause Cancer?
Does meat consumption cause cancer? Or, put another way… does avoiding meat help prevent cancer? If you aren't already savvy to the topic, this may sound more absurd than it should. Here's why: there have been many, many, many correlative studies that have found that higher meat consumption is associated with a significantly higher risk of cancer and cancer mortality. To try to answer this question we end up going deep into discussing plausible mechanisms that might help explain this phenomenon
#032 Does Meat Consumption Cause Cancer?
Does meat consumption cause cancer? Or, put another way… does avoiding meat help prevent cancer? If you aren't already savvy to the topic, this may sound more absurd than it should. Here's why: there have been many, many, many correlative studies that have found that higher meat consumption is associated with a significantly higher risk of cancer and cancer mortality. In this episode, you'll discover: (00:00) Introduction (01:18) How cancer starts (04:49) Growth factors make cancer thrive (08:5
#031 On Depression and Its Underlying Causes
The World Health Organization estimates that more than 350 million individuals of all ages have depression and approximately one-third of all patients with depression fail to respond to conventional antidepressant therapies like SSRI’s. The good news is that today, good science is starting to illuminate the underlying biological mechanisms of depression. This new understanding may soon help the clinical world develop new and more effective treatments. In this episode, you'll discover: (00:00)
On Depression and Its Underlying Causes
The World Health Organization estimates that more than 350 million individuals of all ages have depression and approximately one-third of all patients with depression fail to respond to conventional antidepressant therapies like SSRI’s. The good news is that today, perhaps more than ever, good science is starting to illuminate some of the underlying biological mechanisms surrounding the development of depression. This new understanding may soon help the clinical world develop new approaches to t
#030 Roland Griffiths, Ph.D. on Psilocybin, Psychedelic Therapies & Mystical Experiences
Dr. Roland R. Griffiths Dr. Roland R. Griffiths is a clinical pharmacologist at Johns Hopkins and has been researching mood-altering compounds for over 40 years. As an unusually prolific scientist, having published over 360-times, he's also responsible for having started the psilocybin research program at Johns Hopkins nearly 2 decades ago. In this podcast, you'll discover: (00:00) Introduction (04:05) Psilocybin produces meaningful mind-altering effects (12:52) Psilocybin can treat depressio
Roland Griffiths, Ph.D. on Psilocybin, Psychedelic Therapies & Mystical Experiences
Dr. Roland R. Griffiths is a clinical pharmacologist at Johns Hopkins and has been researching mood-altering compounds for over 40 years. As an unusually prolific scientist, having published over 360-times, he's also responsible for having started the psilocybin research program at Johns Hopkins nearly 2 decades ago. In this 1-hour and 15-minute podcast, we discuss… 00:01:03 - the broader story of Dr. Griffiths 40 years of mood-altering drug research, including what got him started and how taki
Jed Fahey, Sc.D. on Isothiocyanates, the Nrf2 Pathway, Moringa & Sulforaphane Supplementation
Dr. Jed Fahey is a multi-decade veteran of isothiocyanate research and is the director of the Cullman Chemoprotection Center at Johns Hopkins University. Much of this conversation, as you might expect given Dr. Fahey's pedigree as a research scientist, is focused on isothiocyanates and, indeed, sulforaphane! While we covered quite a lot on this very topic (isothiocyanates) via my solo podcast a few weeks ago, this covers everything that may have been overlooked.... and, indeed, so much more! Sk
#029 Jed Fahey, Sc.D. on Isothiocyanates, the Nrf2 Pathway, Moringa & Sulforaphane Supplementation
Dr. Jed Fahey is a multi-decade veteran of isothiocyanate research and is the director of the Cullman Chemoprotection Center at Johns Hopkins University. In this episode, you'll discover: (00:00) Introduction (03:44) What is sulforaphane? (10:25) The NRF2 pathway, a master regulator of antioxidants (14:22) Cruciferous vegetables are rich sources of sulforaphane (20:39) Does cooking broccoli destroy sulforaphane? (26:00) Sulforaphane supplements vary widely in quality (36:41) Antibiotics wipe o
#028 Sulforaphane and Its Effects on Cancer, Mortality, Aging, Brain and Behavior, Heart Disease & More
This podcast is about one of the most important biological pathways you could possibly take the time to learn about: the NRF2 pathway. The most potent naturally-occurring inducer of this pathway, a plant compound known as sulforaphane, may be one of the most potent health-enhancing compounds at our disposal and yet... no one is keeping it out of your hands! No $1,000 per pill markup is keeping it out of your hands -- it’s available to anyone willing to take the little bit of time it takes each w
Sulforaphane and Its Effects on Cancer, Mortality, Aging, Brain and Behavior, Heart Disease & More
This podcast is about one of the most important biological pathways you could possibly take the time to learn about: the NRF2 pathway. The most potent naturally-occurring inducer of this pathway, a plant compound known as sulforaphane, may be one of the most potent health-enhancing compounds at our disposal and yet... no one is keeping it out of your hands! No $1,000 per pill markup is keeping it out of your hands -- it’s available to anyone willing to take the little bit of time it takes each w
#027 Valter Longo, Ph.D. on the Fasting-Mimicking Diet & Fasting for Longevity, Cancer & Multiple Sclerosis
Dr. Valter Longo This episode of the FoundMyFitness podcast features Dr. Valter Longo, a professor of gerontology and biological sciences and director of the longevity institute at the University of Southern California. Dr. Longo has made huge contributions to the field of aging, including the role of fasting and diet in longevity and healthspan in humans as well as metabolic fasting therapies for the treatment of human diseases. In this podcast, Valter and I discuss... (00:00) Introduction (0
Ruth Patterson, Ph.D. on Time-Restricted Eating in Humans & Breast Cancer Prevention
Today's episode features Dr. Ruth Patterson, a professor in the UC San Diego Department of Family Medicine and Public Health as well as Associate Director of Population Sciences and leader of the Cancer Prevention program at Moores Cancer Center at UC San Diego Health. If you enjoyed my last episode with Dr. Satchin Panda, I have good news! This will also be a great episode for you, since we talk about some similar ideas, but focus more on the human side of things, especially when it comes to t
#026 Ruth Patterson, Ph.D. on Time-Restricted Eating in Humans & Breast Cancer Prevention
Dr. Ruth Patterson Dr. Ruth Patterson, a professor in the UC San Diego Department of Family Medicine and Public Health as well as Associate Director of Population Sciences and leader of the Cancer Prevention program at Moores Cancer Center at UC San Diego Health. In this episode, we chat about: (00:00) Introduction (03:33) Lifestyle modifications that reduce breast cancer risk (11:18) Modern life disrupts our circadian rhythm, causing us to eat at odd times (14:31) Women who practiced time-re
Satchin Panda, Ph.D. on Time-Restricted Feeding and Its Effects on Obesity, Muscle Mass & Heart Health
Dr. Rhonda Patrick speaks with Dr. Satchin Panda, a professor at the Salk Institute for Biological Studies in La Jolla California. Satchin's work deals specifically with the timing of food and it's relationship with our biological clocks governed by circadian rhythm and also the circadian rhythm in general. In this video we discuss... The fascinating history of experimentation that ultimately elucidated the location for the region of the brain necessary for a properly timed sleep-wake cycles. T
#025 Dr. Satchin Panda on Time-Restricted Feeding and Its Effects on Obesity, Muscle Mass & Heart Health
Dr. Satchidananda (Satchin) Panda is a professor in the Regulatory Biology Laboratory at the Salk Institute for Biological Studies. In this video we discuss... (00:00) Introduction (06:42) Why humans developed an internal clock (i.e., the circadian rhythm) (15:28) Light is necessary to regulate our circadian clock (25:02) Morning bright light exposure lowers cortisol levels and lifts mood, but the indoors are dim (30:25) Using light exposure to reset jet-lag and help shift workers stay healthy
#024 Ray Cronise on Cold Thermogenesis, Intermittent Fasting, Weight Loss & Healthspan
Ray Cronise Ray Cronise is a former NASA material scientist and cofounder of zero gravity, a company that offers weightless parabolic flights to consumers and researchers. The interesting thing about this interview, isn't strictly raised professional background, however, but instead his propensity towards aggressive self-experimentation. In this episode, Ray and I discuss... (00:00) Introduction (03:40) Ray's 23-day (and counting) water fast (05:13) Using fasting and cold stress to lose weight
Ray Cronise on Cold Thermogenesis, Intermittent Fasting, Weight Loss & Healthspan
Dr. Rhonda Patrick speaks with
Ray Cronise, a former NASA material scientist and cofounder of zero
gravity, a company that offers weightless parabolic flights to
consumers and researchers. In this episode, coming at the tail end
of a rather extreme 23-day water fast for Ray, we discuss, perhaps
unsurprisingly, some of the benefits that are associated with
fasting! Ray talks about
shifting one's perspective from looking at nutrition only through
the lens of meeting day-to-day nutritional needs, a
#023 Dominic D'Agostino, Ph.D. on Modified Atkins Diet, Ketosis, Supplemental Ketones and More
Dr. Dominic D'Agostino This podcast is with Dr. Dominic D'Agostino, an assistant professor at the University of South Florida in Tampa and all-around expert on ketosis. In this podcast we discuss: (00:00) Introduction (03:46) Ketosis has abundant therapeutic potential (10:20) What to eat to maintain nutritional ketosis (19:58) Does a high-fat diet harm the gut? (29:14) Adaptations to a ketogenic diet expand mitochondrial capacity (38:45) How the brain uses ketones (46:36) Ketones improve Alzhe
Dominic D'Agostino, Ph.D. on Modified Atkins Diet, Ketosis, Supplemental Ketones and More
This podcast is with Dr. Dominic D'Agostino, an assistant professor at the University of South Florida in Tampa and all around expert on ketosis.
In this podcast we discuss...
* Dom's efforts at teasing out the differences between induced nutritional ketosis (through a low carbohydrate, high fat diet) and ketosis from the dietary introduction of exogenous ketones, like beta-hydroxybutyrate, especially in the context of therapeutic and performance enhancing effects.
* His work
#022 Peter Attia, M.D. on Macronutrient Thresholds for Longevity & Performance, Cancer & More
Dr. Peter Attia Peter is the founder of Attia Medical, a medical practice with offices in San Diego and New York City, focusing on the applied science of longevity and optimal performance. In addition to being a medical doctor, Dr. Attia has done research on the role of regulatory T cells in cancer regression and other immune-based therapies for cancer. Regulatory T cells have also been, in the past, referred to as suppressor T cells because of their role in actually attenuating or reducing the
Peter Attia, M.D. on Macronutrient Thresholds for Longevity & Performance, Cancer & More
This podcast is with Dr. Peter Attia. Peter is the founder of Attia Medical, a medical practice with offices in San Diego and New York City, focusing on the applied science of longevity and optimal performance.
You may have first heard about Dr. Attia from his two interviews that have been on the Tim Ferriss show, or from any number of popular presentations he's given that were filmed and put online. In addition to being a medical doctor, Dr. Attia has done research on the role of regul
#021 How Cryotherapy Affects the Brain, the Immune System, Metabolism, and Athletic Performance
Dr. Rhonda Patrick explains how cold shock is a type of hormesis, which is a description of a type of stress that, in the right doses, is enough to shock the body and kick off adaptive processes and response mechanisms that are hardwired into our genes, and, once on, are able to create a resilience that actually exceeds what was needed to counter the initial stimuli. In this episode, you'll discover: (00:00) Introduction (03:09) Cold exposure is good stress for the brain (15:42) Cryotherapy red
How Cryotherapy Affects the Brain, the Immune System, Metabolism, and Athletic Performance
This podcast has a 20-page report associated with it! Get it now at foundmyfitness.com/cryotherapy. Dr. Rhonda Patrick explains how cold shock is a type of hormesis, which is a description of a type of stress that, in the right doses, is enough to shock the body and kick off adaptive processes and response mechanisms that are hardwired into our genes, and, once on, are able to create a resilience that actually exceeds what was needed to counter the initial stimuli. Rhonda discusses how cold expo
#020 Rich Roll on Self-Transformation, Environmental Impact of Food, and the Plant-Based Diet
Rich Roll This podcast features Rich Roll. Rich is an author, a podcaster ("Rich Roll Podcast" on iTunes), as well as founder and first person to complete the EPIC5 Challenge. The EPIC5 challenge involves completing 5 Full Iron Distance triathlons on 5 Hawaiian islands in under a week. Rich has also been a repeated top finisher in the Ultraman World Championships in Hawaii, which is a three-day, 515km (320 mile) annual endurance race held on the Big Island of Hawaii. You can read about Rich's j
Rich Roll on Self-Transformation, Environmental Impact of Food, and the Plant-Based Diet
This podcast features Rich Roll. Rich is an author, a podcaster ("Rich Roll Podcast" on iTunes), as well as founder and first person to complete the EPIC5 Challenge. The EPIC5 challenge involves completing 5 Full Iron Distance triathlons on 5 Hawaiian islands in under a week. Rich has also been a repeated top finisher in the Ultraman World Championships in Hawaii, which is a three-day, 515km (320 mile) annual endurance race held on the Big Island of Hawaii. The race is divided into three stages
#019 Dr. Darya and Kevin Rose Talk Meditation Retreats, Diet, Seasonal Eating, and More
In this episode, Dr. Rhonda Patrick chats with Dr. Darya and Kevin Rose. Dr. Darya Rose, PhD is a neuroscientist, author of “Foodist: Using Real Food and Real Science to Lose Weight Without Dieting,” and creator of Summer Tomato, which was featured in TIME magazine’s list of the web’s 50 best websites in 2011. Kevin you may know from TV, the investing world, or any of a wide variety of things he’s well known for (founding digg.com, just for starters). More recently, Kevin hosts a podcast where h
Dr. Darya and Kevin Rose Talk Meditation Retreats, Diet, Seasonal Eating, and More
In this episode, Dr. Rhonda Patrick chats with Dr. Darya and Kevin Rose. They chat about Darya's fascinating experience on a 10-day silent meditation retreat where she spent around 7 hours a day doing seated meditation, intermingled with another 6 hours a day of walking meditation. They discuss the biological significance of mindfulness while eating, unlocking the mysteries of blood glucose by actually testing your response to foods, or, in Kevin's case, alcoholic beverages. Kevin talks about hi
#018 Dr. Pierre Capel on the Power of the Mind & the Science of Wim Hof
Dr. Pierre Capel Dr. Pierre Capel is a professor emeritus in experimental immunology at the Utrecht University in the Netherlands where he researched a wide range of topics from genetic modification to cancer immunotherapy. Pierre also works with Wim Hof, otherwise known as the iceman (guest on the last podcast) who is especially well-known for some of his amazing physical feats, like staying in a tub with direct contact to ice for over an hour and fifty three minutes. Pierre explains some of th
Dr. Pierre Capel on the Power of the Mind & the Science of Wim Hof
Dr. Rhonda Patrick interviews Dr. Pierre Capel, professor emeritus in experimental immunology at the Utrecht University in the Netherlands where he researched a wide range of topics from genetic modification to cancer immunotherapy. Pierre also works with Wim Hof, otherwise known as the iceman (guest on the last podcast) who is especially well-known for some of his amazing physical feats, like staying in a tub with direct contact to ice for over an hour and fifty three minutes. Pierre explains s
#014 Wim Hof (the Iceman) on Defeating Extreme Cold & Attenuating the Immune Response
Wim Hof Wim Hof also known as the "Iceman." Wim holds the world record for the longest ice bath (1 hour and 53 minutes and 12 seconds), just to name one of his many impressive feats. Dr. Patrick and Wim talk a bit about Wim's back story that culminated in him trying out cold water immersion, the relatively recent 2014 scientific publication of the “Wim Hof Method” which includes cold exposure during training, exposure to bacterial endotoxin, Wim's breathing techniques, and meditation (http://www
#017 Wim Hof (the Iceman) on Defeating Extreme Cold & Attenuating the Immune Response
Wim Hof Wim Hof, also known as "the Iceman", holds the world record for the longest ice bath (1 hour and 53 minutes and 12 seconds), just to name one of his many impressive feats. Dr. Patrick and Wim talk a bit about Wim's back story that culminated in him trying out cold water immersion, the relatively recent 2014 scientific publication of the "Wim Hof Method" which includes cold exposure during training, exposure to bacterial endotoxin, Wim's breathing techniques, and meditation. In this episo
Wim Hof (the Iceman) on Defeating Extreme Cold & Attenuating the Immune Response
Dr. Rhonda Patrick interviews Wim Hof also known as the "Iceman." Wim holds the world record for the longest ice bath (1 hour and 53 minutes and 12 seconds), just to name one of his many impressive feats. Dr. Patrick and Wim talk a bit about Wim's back story that culminated in him trying out cold water immersion, the relatively recent 2014 scientific publication of the “Wim Hof Method” which includes cold exposure during training, exposure to bacterial endotoxin, Wim's breathing techniques, and
PRESENTATION: Rhonda Speaks at the Orthomolecular Congress in Bussum, Netherlands
In this audio recorded Oct. 3rd, 2015, Dr. Rhonda Patrick delivers the keynote lecture at the Orthomolecular Medicine Congress in Bussum, Netherlands (MBOG Congres 2015).
Discussion includes how micronutrient inadequacies are very prevalent, and how her mentor, Dr. Bruce Ames, found that the body does a strategic rationing so that those proteins and enzymes in the body which are essential for short-term survival get their share of vitamins and minerals at the expense of other proteins
#016 PRESENTATION: Rhonda Speaks at the Orthomolecular Congress in Bussum, Netherlands
Dr. Rhonda Patrick delivers the keynote lecture at the Orthomolecular Medicine Congress in Bussum, Netherlands (MBOG Congres 2015). In this talk, you'll learn about: (00:00) Introduction (04:52) Micronutrient inadequacies and triage theory (10:42) Role of DNA damage in cancer and aging (21:10) Vitamin D, serotonin, and the development of autism (41:39) Omega-3s also regulate serotonin If you’re interested in learning more, you can read the full show notes here. Join over 300,000 people and ge
#015 Buffering the Negative Effects of Chronic Stress with Meditation
In this podcast, I discuss some of the mechanisms by which chronic stress (and rumination) affect health and aging and how meditation can reduce rumination and buffer stress. In this episode, you'll discover: (00:00) Introduction (02:41) Eustress such as exercise vs distress such as fear (06:15) Effects of stress on the brain (07:30) Effects of stress on the gut and microbiome (10:21) Stress accelerates biological aging (15:04) Meditation reduces rumination and promotes empathy (19:53) Effects
Buffering the Negative Effects of Chronic Stress with Meditation
In this podcast I discuss some of the mechanisms by which chronic stress (and rumination) affect the brain and brain aging, the gut and inflammation, the immune system, and biological aging through acceleration of telomere shortening. I talk about how meditation can buffer these negative effects of stress and improve cognitive performance, brain aging and biological aging in general. Get the free report: foundmyfitness.com/meditation-report
#014 Sauna Use and Building Resilience to Stress with Dr. Rhonda Patrick
In this episode Rhonda talks about: (00:00) Introduction (03:00) Heat stress makes the body more resilient to the stresses of aging (14:45) Possible mechanisms why sauna use reduces heart disease risk (16:45) Sauna enhances athletic endurance and muscle growth (28:16) Sauna use stimulates neurogenesis and improves cognitive function and mood (37:34) Sauna use detoxifies BPA, PCBs, phthalates, and other metals (51:10) Practical applications sauna use and other heat stressors like hot yoga If yo
Sauna Use and Building Resilience to Stress with Dr. Rhonda Patrick
In this episode Rhonda talks about how heat stress from using the sauna makes the body more resilient to the stresses of aging, possible reasons why one study associated sauna use with up to a 40% lower all-cause mortality as well as a 50% lower cardiovascular disease related mortality, how it enhances athletic endurance, staves off muscle atrophy, improves regrowth of muscle after disuse, and some of the profound effects on the brain, including the growth of new brain cells, improvement in focu
#013 How The Gut Microbiota Affects Our Health with Dr. Erica & Dr. Justin Sonnenburg
Dr. Justin Sonnenburg Dr. Justin Sonnenburg is an associate professor of microbiology and immunology at Stanford and Dr. Erica Sonnenburg is a senior research scientist in the Sonnenburg lab where they research many aspects the interaction between diet with the 100 trillion or so bacteria in the gut (specifically the colon) and how this impacts the health of the host (which in this case is a laboratory research mouse). In this episode, we discuss... (00:00) Introduction (02:50) What is the gu
The Sonnenburgs On How The Gut Microbiota Interacts With Our Bodies
Dr. Justin Sonnenburg is an associate professor of microbiology and immunology at Stanford and Dr. Erica Sonnenburg is a senior research scientist in the Sonnenburg lab where they research many aspects the interaction between diet with the 100 trillion or so bacteria in the gut (specifically the colon) and how this impacts the health of the host (which in this case is a laboratory research mouse). In this episode we discuss the pivotal role fiber plays in fueling good bacteria in the gut to prod
#012 Dr. Ronald Krauss on LDL Cholesterol, Particle Size, Heart Disease & Atherogenic Dyslipidemia
Dr. Ronald Krauss Dr. Ronald Krauss, M.D. is the director of atherosclerosis research at Children’s Hospital Oakland Research Institute, Adjunct Professor at UCSF and UC Berkeley. Dr. Krauss is really one of the pioneering scientists that changed the way we all think about cholesterol and saturated fat. He developed an assay that allows the quantification of low density lipoprotein particle size and concentration (known to the wider world as LDL cholesterol) based on a technique which determines
Ron Krauss on Re-thinking Saturated Fat & LDL Cholesterol
Dr. Ronald Krauss, M.D. is the director of atherosclerosis research at Children’s Hospital Oakland Research Institute, Adjunct Professor at UCSF and UC Berkeley. Dr. Krauss is really one of the pioneering scientists that changed the way we all think about cholesterol and saturated fat. He developed an assay that allows the quantification of low density lipoprotein particle size and concentration (known to the wider world as LDL cholesterol) based on a technique which determines the size of the p
CHORIBar: Micronutrients, Fiber & Polyphenols in a Bar
Meet some of the CHORI bar team: Dr. Bruce Ames, Dr. Joyce McCann, and Dr. Mark Shigenaga. On this podcast we talk about the different types of HDL and LDL cholesterol and what they do in the body. We discuss a low-calorie, micronutrient- and fiber-dense nutrition bar (referred to as the CHORI bar) that Bruce and I briefly touched on in a previous conversation, how each of the components of the bar from the vitamins and minerals to the fiber and polyphenols are all really important but have sepa
#011 CHORIBar: Micronutrients, Fiber & Polyphenols in a Bar
CHORI Bar Team Meet some of the CHORI bar team: Dr. Bruce Ames, Dr. Joyce McCann, and Dr. Mark Shigenaga. On this podcast we talk about the different types of HDL and LDL cholesterol and what they do in the body. We discuss a low-calorie, micronutrient- and fiber-dense nutrition bar (referred to as the CHORI bar) that Bruce and I briefly touched on in a previous conversation, how each of the components of the bar from the vitamins and minerals to the fiber and polyphenols are all really importan
Dr. Aubrey de Grey and Dr. Rhonda Patrick Talk Aging
Dr. Aubrey de Grey is a biomedical gerontologist and the founder of the SENS research foundation which aims to find technologies that can repair the various types of damage that occur during the aging process. In this episode Rhonda and Aubrey discuss the types of damage that cause aging, how aging results in a decrease in the capacity to repair damage, what role epigenetics play in aging, how people age at different rates, chronic inflammation as a driver of aging, factors that are in young blo
#010 Dr. Aubrey de Grey and Dr. Rhonda Patrick Talk Aging
Dr. Aubrey de Grey Dr. Aubrey de Grey is a biomedical gerontologist and the founder of the SENS research foundation which aims to find technologies that can repair the various types of damage that occur during the aging process. In this episode, we discuss... 00:00:00 - Introduction 00:02:27 - How to understand aging 00:08:14 - Epigenetic modifications accommodate cellular aging 00:18:24 - Inflammation is a double-edged sword 00:24:00 - Parabiosis has the potential to slow aging 00:31:35 - Li
#009 Rhonda Answers the Most Popular Questions About Vitamin D
Dr. Rhonda Patrick answers some of the most popular questions regarding vitamin D including: (00:00) Introduction (02:22) How do you decide how much vitamin D to supplement with? (12:51) Is it possible to get too much vitamin D? (20:52) Is there a difference between vitamin D made from the sun versus a supplement? (24:43) What form of vitamin D is more bioavailable or absorbed better? Join over 300,000 people and get the latest distilled information straight to your inbox weekly: https://www.f
Rhonda Answers the Most Popular Questions About Vitamin D
Dr. Rhonda Patrick answers some of the most popular questions regarding vitamin D including:
- How she decides how much vitamin D to supplement with
- Can you get too much vitamin D
- Is there a difference in vitamin D made from the sun versus a supplement
- What form of vitamin D is more bioavailable or absorbed better.
#008 Sleep, Daylight Anchoring, and Effects on Memory & Obesity with Dan Pardi
Dan Pardi Dr. Dan Pardi researches sleep neurobiology and is a co-founder of Dan’s Plan, an online wellness and technology company. In this episode, we discuss... (00:00) Introduction (03:27) Circadian rhythms are key to health (07:07) Artificial lights suppress melatonin production (12:04) Sleep clears toxins from the brain (16:14) Sleep deprivation increases appetite and decreases energy expenditure (24:09) Sleep is critical for creating long-term memories (31:29) Blue light can reset circad
Dan Pardi on the Consequences of Sleep Loss & Ways to Improve Sleep
Dan Pardi is a Ph.D candidate that researches sleep neurobiology at Stanford and University of Leiden. He is also co-founder of Dan’s Plan, an online wellness and technology company. In this podcast Rhonda and Dan discuss what the determinants of good sleep are including duration, timing and intensity,the major causes of less sleep in our society, the consequences of sleep loss including decreased purging of toxic substances from the brain, damage to neurons that signal to the brain to stay awa
Tim Ferriss on Biomarkers, Ketosis, Microbiome, and Lyme Disease
Tim Ferriss, notorious self-experimenter, three-time New York Times bestselling author, an angel investor, startup advisor, and much, much, much more. Full audio transcript available at: http://wwww.foundmyfitness.com/timtranscript
#007 Tim Ferriss on Biomarkers, Ketosis, Microbiome, and Lyme Disease
Tim Ferriss Tim Ferris is a notorious self-experimenter, three-time New York Times bestselling author, angel investor, startup advisor, and much, much, much more. In this episode, we discuss... (00:00) Introduction (02:29) Oxytocin, vasopressin, and the neuroendocrine basis of pair bond formation (05:54) Tim’s self-experimentation with the ketogenic diet and the biomarkers he measures daily (14:55) Can a ketogenic diet reduce Alzheimer’s disease risk? (22:14) Inflammation accelerates aging, b
#006 Jim Kean Talks Biomarkers, Building a Spectator Sport
Jim Kean Jim Kean is the CEO of National Pro Grid League (NPGL) and founder of WellnessFX. In this podcast Rhonda and Jim discuss the quantified self movement and the importance of measuring biomarkers more than once, the gut's role in cholesterol and serotonin in the gut versus in the brain, about the role of exercise in preventing neuroinflammation and the effects of overtraining on sex hormones. We also chat a bit about the psychology of constructing a new, non-gender segregated, team spectat
Jim Kean Talks Biomarkers, Building a Spectator Sport
Jim Kean is the CEO of National Pro Grid League (NPGL) and founder of WellnessFX. In this podcast Rhonda and Jim discuss the quantified self movement and the importance of measuring biomarkers more than once, the gut's role in cholesterol and serotonin in the gut versus in the brain, about the role of exercise in preventing neuroinflammation and the effects of overtraining on sex hormones, a bit about the psychology of constructing a new, non-gender segregated, team spectator sport and bringing
Dr. Bruce Ames Talks CHORI-Bar Weight Loss
Dr. Rhonda Patrick speaks with Dr. Bruce Ames, about a micronutrient- and fiber-dense nutrition bar (referred to as the CHORI bar) that was developed in the Ames laboratory. The bar was formulated to be moderate in calories (107 kcal/≈25 g bar), but nutrient dense, with a polyphenolic-rich matrix of fruit, walnuts, and non-alkali-processed dark chocolate, supplemental vitamins, minerals, docosahexaenoic acid (DHA), a blend of insoluble and soluble fibers, protein, and glutamine. Most vitamins an
#005 Dr. Bruce Ames Talks CHORI-Bar Weight Loss
Dr. Bruce Ames Dr. Rhonda Patrick speaks with Dr. Bruce Ames, about a micronutrient- and fiber-dense nutrition bar (referred to as the CHORI bar) that was developed in the Ames laboratory. The bar was formulated to be moderate in calories (107 kcal/≈25 g bar), but nutrient dense, with a polyphenolic-rich matrix of fruit, walnuts, and non-alkali-processed dark chocolate, supplemental vitamins, minerals, docosahexaenoic acid (DHA), a blend of insoluble and soluble fibers, protein, and glutamine. M
Bruce Ames on Triage Theory, Longevity Vitamins & Micronutrients
In this podcast Dr. Rhonda Patrick interviews Dr. Bruce Ames about his triage theory, which he proposes that the body has developed a rationing response to shortages of micronutrients (vitamins and minerals) throughout evolution. When cells run out of a vitamin or mineral, that scarce micronutrient is allotted to proteins (in the body) essential for short-term survival. Proteins needed for long-term health, including those that protect DNA, lose out and become disabled and lead to diseases of ag
#004 Bruce Ames on Triage Theory, Longevity Vitamins & Micronutrients
Dr. Bruce Ames In this podcast, Dr. Rhonda Patrick interviews her mentor, Dr. Bruce Ames, about his triage theory and other nutrition topics. Dr. Ames was the 23rd most-cited scientist between 1973 and 1984, which is evidence of his long and productive career investigating human health and disease. Dr. Ames continues his research expanding our knowledge of nutrients such as vitamin D and its role in Autism spectrum disorder. In this episode, we discuss... 00:00:00 - Introduction 00:04:18 - Dr.
#003 5 to 7x More Stem Cells from Placenta with Dr. Frans Kuypers
In this interview, Dr. Rhonda Patrick talks to Dr. Frans Kuypers about his lab’s discovery on how the human placenta is a rich source of pluripotent stem cells, and yet the placenta is thrown away after delivery. In this episode, we discuss... 00:00:00 - Introduction 00:04:39 - The human placenta as a source of hematopoietic cells 00:11:30 - Pluripotent cells can differentiate into any cell in the human body 00:13:03 - Public banking of abundant pluripotent placental stem cells 00:18:06 - The
#002 Dr. George Brooks on Lactate Shuttle Theory, Relevance for Traumatic Brain Injury, and More
Dr. George A Brooks Dr. George A Brooks, an expert in exercise physiology and lactate metabolism. Lactate, a once demonized molecule thought to form lactic acid and become a dead-end toxic metabolite, has been vindicated by the work of Dr. Brooks, his colleagues, and others. In this episode, we discuss... (00:00) Introduction (01:40) Dr. Brooks’ experience as an athlete inspired his research on lactate (06:50) Lactate and its relationship to muscle fatigue is misunderstood (09:10) Adaptations
#001 Dr. Terry Wahls' Protocol That Reversed Multiple Sclerosis
In this video Dr. Rhonda Patrick interviews Dr. Terry Wahls about how she reversed her secondary-progressive multiple sclerosis with a micronutrient-dense diet and Paleo principles. She identified vitamins/minerals and other compounds present in vegetables/fruits that are essential for mitochondrial health, which is critical for brain function. In this episode, we discuss... (00:00) Introduction (00:48) Dysfunctional mitochondria contribute to disease development (04:03) Suboptimal magnesium